Clinical Presentations, Risk Factors and Type of Endometrial Cancer in Relation to Endometrial Thickness in Tumour Therapy and Cancer Research Centre Shendi University

Abstract

Background: Endometrial cancer is the most frequent ontological pathology in postmenopausal disassociated with abnormal uterine bleeding. Different studies have found a significant relationship between increased endometrial thickness and the risk of EC. Objectives: We aimed to study an endometrial cancer clinical presentation, factor and the type of endometrial cancer in relation to the endometrial thickness, in tumor therapy and cancer research center (TTCRC) in Shendi city. Methodology: This is a descriptive cross-sectional Hospital–based study including 120 Sudanese women attend the (TTCRC), the data were collected by questionnaire from histopathology laboratory and medical statistical department. Results: The mean age of our participants was 57.9± years. Multi 78 porous was observed in 64 cases (53.3%), Obesity (≥30–39.9BMI) in 43cases (35.8%), just12cases (10%) had family history with EC, and post-menopausal bleeding in 47 cases (39.5%). There were 68 cases (56.7%) of Aden carcinoma (with squamous differentiation) and 40 cases (33.3%) their endometrial thickness 4- 10 mm. There were significant association between endometrial thickness and, type EC (all P<0.05), and significant with age and clinical presentation (P=0.027). Conclusion: the in cadence of EC in the patients was higher in age >50 years, Multi-parous, BMI ≥ 30kg/m2, PMB was higher ate clinical presentation, Aden carcinoma (with squamous differentiation were common type of EC, most of the cases the in endometrial thickness were 4-10 mm and we found significant association with Type EC. Keywords: Endometrial Cancer, Shendi, Sudan