Association of EBV in Gastric carcinoma among Sudanese patients

Abstract

Background: Gastric cancer is the second most common gastrointestinal cancer and is largely attributed to Helicobacter pylori (H. pylori) infection. In addition, studies have also shown association with Epstein-Barr virus (EBV) in 10% of gastric cancers. The aim of this review was to estimate the present of EBV in gastric cancer among Sudanese patients. Material and Methods: In this is descriptive retrospective study, which carried out in Omdurman teaching hospital Khartoum-Sudan, involved 30 surgically treated formalin-fixed, paraffin embedded tumor samples from patients with gastric cancer, collected during January 2014 and October2015. The presence of EBV in was determined using immunohistochemistry Result; the study involved (30) subject 71 was male (56, 6) while 77 was female (36, 6) with (1.6: 1) males: female ratio, ten sample were positive (23.3) while 20 sample (76, 7) was negative, with no statistically significant difference between EBV infection and type of tumors. Conclusion: high association of EBV and gastric cancer was reported in this study.