CORRELATION BETWEEN ERYTHROCYTE SEDIMENTATION RATE AND C – REACTIVE PROTEIN IN ARTHRITIS PATIENTS IN SHENDI LOCALITY – RIVER NILE STATE

Abstract

Background: Erythrocyte sedimentation rate (ESR) and serum of C-reactive protein (CRP) are the acute phase reactants most commonly determined in patients with rheumatic diseases. The indices are affected by different factors, but both of them are applied for evaluation of the disease activity in patients with inflammatory disorders of the musculoskeletal system. Methods: This is a cross-sectional case control prospective analytical study conducted in shendi town to identify the correlation between erythrocyte sedimentation rate and C-reactive protein in arthritis patients in the period between (March to May2018). Venous blood collected using sterile disposable plastic syringe after, 2.5ml of venous blood for ESR citrated blood was added to the anticoagulant and gently mix, while CRP blood was collected in EDTA. Results: The result of this study showed that the mean of ESR in test group was (71mm/h), while in control group was (19mm/h), and the mean of CRP in test group was (18mg/l), while in control group was (3.0 mg/l). Also the result of this study demonstrated that the mean of ESR and CRP level was higher in that group of age more than 40 years. Conclusion: From this study it appears that there was significant variation in CRP and ESR when compared the test group with control group.