Abstract:
Background: Gastric cancer is the second most common gastrointestinal cancer and is largely attributed to Helicobacter
pylori (H. pylori) infection. In addition, studies have also shown association with Epstein-Barr virus (EBV) in 10% of gastric
cancers. The aim of this review was to estimate the present of EBV in gastric cancer among Sudanese patients.
Material and Methods: In this is descriptive retrospective study, which carried out in Omdurman teaching hospital
Khartoum-Sudan, involved 30 surgically treated formalin-fixed, paraffin embedded tumor samples from patients with gastric
cancer, collected during January 2014 and October2015. The presence of EBV in was determined using
immunohistochemistry
Result; the study involved (30) subject 71 was male (56, 6) while 77 was female (36, 6) with (1.6: 1) males: female ratio, ten
sample were positive (23.3) while 20 sample (76, 7) was negative, with no statistically significant difference between EBV
infection and type of tumors.
Conclusion: high association of EBV and gastric cancer was reported in this study.
